The company behind the Citywest Hotel, which is owned by private equity group Tetrarch Capital, has been refused permissio n to hold concerts at the venue despite pleading to An Bord Pleanála that the events would attract an older demographic than other music venues.
Live Nation, the US events promoter, had been lined up to manage concerts.
Cape Wrath, the firm behind the hotel, was refused permission at the beginning of this year by South Dublin County Council to hold concerts at the property.
The council rejected the plan because of concerns that the volume of traffic attending concerts could cause congestion on the surrounding road network.
Cape Wrath appealed the decision to An Bord Pleanála, which has also rejected the plans.
Transport Infrastructure Ireland told the planning watchdog it had concerns that extra traffic could adversely affect the safety of the national road network.