The Chief Medical Officer has said it is time for people to "feel hopeful" and to start planning their summer.
From next week inter-county travel resumes for the first time since Christmas, while up to three households can meet outdoors, including in private gardens.
Non-essential retail reopens for click-and-collect, as well as for appointment-only shopping in-store, while personal services such as barbers and hairdressers can also resume trading on an appointment basis.
Galleries, museums, libraries and other cultural attractions can reopen, and adult sports training can resume outdoors in pods of 15.
"We all want the easing of restrictions next week to be a significant turning point in this pandemic," Dr Tony Holohan has said.
"We have worked so hard to reduce the spread of this disease. More than 30% of adults have now been vaccinated with one dose of Covid-19 vaccine in Ireland and it is time to feel hopeful and to start planning our summer.